David Highton

Effects of continuing or withholding angiotensin axis blockers prior to elective surgery: The PAAB randomized clinical trial

Abstract Background Current guidelines favour preoperative withholding of angiotensin‐axis blockers (AABs) in patients without hypertension or systolic heart failure to decrease peri‐operative cardiorenal risk, although evidence of such effects is lacking. Objective To assess rat...

Implementing univerSal TeleprehabiliTation into cAnceR caRe pathwayS (STTARRS Trial): protocol for a hybrid type 1 multi-centre randomised controlled trial and nested sub study

Abstract Background Postoperative complications are common after major cancer surgeries, occurring in 25–50% of patients. They delay recovery and adversely affect both cancer-free and overall survival. Intervention to optimise patients’ physical and psychological wellbeing before...