David Crich

Energeticsof Formation and Fragmentation of Carbon-CenteredRadicals α- to Nitrogen and Oxygen in N , N , O -Trimethylhydroxylamine in Comparisonto Trimethylamine and Dimethyl Ether: Implications for Medicinal andSynthetic Chemistry

Abstract α–C–H bond dissociation energies (BDEs) have been computed for N,N,O-trimethylhydroxylamine, trimethylamine, and dimethyl ether, leading to the conclusion that there is no advantage to hydrogen abstraction from trisubstituted hydroxylamines over the corresponding tertiar...