David A. Nagib

Remote Desaturation of Unprotected Amines and C─H Amination of Alkanes by Polarity‐Matched N‐Radical Cations

ABSTRACT A CuCl‐catalyzed strategy enables practical, selective, and efficient δ desaturation of unprotected amines. These bifunctional molecules allow rapid conversion of simple amines to privileged heterocycles in medicine. The key radical relay mechanism is an interrupted Hofm...