Dave VanInsberghe

Ligninase Activity Is Not Consistently Predicted by the Presence of Manganese Coordinating Residues in Dyp-like Proteins

DypB, a characterized bacterial lignin peroxidase from Rhodococcus jostii RHA1, is thought to modify lignin using oxidized manganese as a diffusible mediator. Structural analysis has determined that manganese is bound and oxidized through a pocket near the active site that is com...