Danny van Noort

Microfluidic Cytotongue system enables early, label-free detection of CAR-T–induced mechanical softening in tumor spheroids

Quantitative assessment of chimeric antigen receptor T (CAR-T) activity in solid tumors remains challenging, as immune engagement can induce early mechanical softening of tumor spheroids before overt cell death becomes detectable. To address this limitation, we developed Cytotong...