Danlei Chen

Senescent pulmonary epithelial cells-derived S100A10 drives epithelial-fibroblast crosstalk through inhibiting vimentin ubiquitination in pulmonary fibrosis

Pulmonary fibrosis is a chronic, lethal, and ageing-associated interstitial lung disease of unknown aetiology, involves pulmonary epithelial cell senescence and fibroblast activation. However, the underlying mechanism remains elusive. This study aims to investigate the role and p...