Daniele Giardiello

The Impact of the Number and the Size of Clusters on Prediction Performance of the Stratified and the Conditional Shared Gamma Frailty Cox Proportional Hazards Models

ABSTRACT Researchers in biomedical research often analyze data that are subject to clustering. Development and validation of risk prediction models generally assumes independence of observations. For survival outcomes, the Cox proportional hazards (PH) regression model is commonl...