Daniel Kacy Cullen

Bioengineered microtissue model of the human nigrostriatal pathway featuring centimeter-scale axon tracts and structural maturation over 6 months in vitro

The basal ganglia (BG) comprise a critical neural system involved in voluntary motor coordination and balance. While small animal models have been useful to improve our basic understanding of the development and function of neural systems, they are relatively low-throughput, lack...