Daniel Idoate Domench

Factor V Deficiency and Mechanical Valve Replacement: Challenges in Perioperative Hemostasis and Anticoagulation.

Factor V deficiency is a rare autosomal recessive bleeding disorder marked by impaired thrombin generation and variable bleeding risk. Perioperative management becomes particularly challenging in high-risk surgeries, such as aortic valve replacement, due to the absence of targete...