Daniel Boy-Ruiz

NLRP1 Inflammasome is Associated to IL-18 in Familial Mediterranean Fever and MEFV Variants

Abstract “Familial Mediterranean Fever (FMF) (OMIM #249,100) is the most prevalent hereditary autoinflammatory disease globally, though it remains rare outside Mediterranean populations. FMF is caused by gain-of-function mutations in the MEFV gene, which encodes the immune regula...