Daniel Abebayehu

Extracellular matrix composition and stiffness regulates progesterone responsiveness and decidualization

Endometriosis is an inflammatory disease of endometrium found outside the uterus. Approximately a third of patients remain unresponsive to hormonal treatments due to progesterone resistance. Because endometriosis lesions are found within fibrotic extracellular matrix (ECM), we hy...