Dan Lythgoe

In vitro activity of gepotidacin against baseline Neisseria gonorrhoeae phenotypes and genotypes recovered from a clinical trial for uncomplicated urogenital gonorrhea (EAGLE-1)

ABSTRACT There is an urgent need for novel antimicrobials to treat multidrug-resistant strains of Neisseria gonorrhoeae . In a phase III trial (EAGLE-1), gepotidacin, a first-in-class triazaacenaphthylene antibacterial, demonstrated non-inferiority to ceftriaxone plus azithromyci...