Damien Daniel Pearse

Replace, Reprogram, and Relay: A Framework for Glial Cell and Extracellular Vesicle Therapies in CNS Repair

Glial cells shape inflammatory resolution, metabolic support, debris clearance, axonal preservation, and myelin repair after CNS injury and neurodegeneration. These functions have motivated two related but non-equivalent therapeutic strategies, either the transplantation and repl...