Daisuke Hisamatsu

Leveraging the salivary microbiome profile to stratify REM sleep behavior disorder and synucleinopathies

Abstract Few studies have explored noninvasive biomarkers of synucleinopathies, including Parkinson’s disease (PD), and rapid-eye-movement behavior disorder (RBD), a prodromal stage for these conditions. Human oral/salivary microbiomes are altered in PD, highlighting their potent...