Curtis M. Tatsuoka

Modeling the heterogeneity of cognitive dysfunction in Parkinson’s disease using partially ordered set models

Abstract Traditional binary classifications of Parkinson’s disease (PD) cognitive dysfunction fail to capture its inherent heterogeneity. This study introduces the Partially Ordered Set (POSET) model, a Bayesian framework, to analyze cognitive heterogeneity using Parkinson’s Prec...

Functionally active lymphoid aggregates correlate with improved prognosis in brain metastases

Abstract B cells and their cellular neighborhoods, i.e., lymphoid aggregates (LAs) and tertiary lymphoid structures (TLS), have not been extensively studied in melanoma brain metastases (BM) or lung adenocarcinoma (LUAD) BM, despite their prognostic value and role in immunotherap...