Colin Bonduelle

Antibacterial Cyclic Oligo(disulfide)s with Tunable Hydrophilicity Dictate Membrane Interactions and Distinct Metabolic Interference

Abstract To combat drug-resistant bacteria, antimicrobial agents with tunable and multi-modal mechanisms are urgently needed. While membrane-disrupting polymers have been widely explored, precisely regulating their membrane interactions and downstream metabolic effects remains ch...

Polyproline: A Synthetic Polypeptide With Unique Properties

Polyproline is a unique polypeptide defined by its unusual conformational rigidity and physicochemical behavior. Addressing long-standing challenges in its synthesis and characterization, this mini-review highlights recent advances in the ring-opening polymerization of proline N-...