Claudio Luchini

Transcriptome Dynamics From Primary Gastric Cancer to Peritoneal Metastases: Translational Insights for Surgical Oncology

BACKGROUND AND AIMS: Peritoneal metastases (PMs) represent the most frequent, clinically challenging dissemination pattern in advanced gastric cancer, especially poorly cohesive (PCGC) subtype, and are associated with poor prognosis. We aimed to characterize the transcriptomic la...

Pancreatic ductal adenocarcinoma and its subtypes: clinical relevance of histopathology and molecular characterization, integrating the key updates of the 2026 WHO classification

Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers, due to its late clinical presentation, early vascular, perineural, nodal and distant dissemination, and profound resistance to systemic therapies. Histologically, conventional PDAC is charac...