Clarice S. Groeneveld

FastCNV: fast and accurate copy number variation prediction from high-definition spatial transcriptomics and scRNA-seq data

Abstract Background Predicting DNA copy number variations (CNVs) from spatial transcriptomics (ST), including Visium HD, or single-cell RNA-sequencing (scRNA-seq) data helps to distinguish malignant from non-malignant cells and to characterize the clonal architecture of tumor cel...