Chunyan Zhang

Atractylodis Rhizoma-derived nanovesicles suppress adipocyte IDO1/kynurenine-AhR-androgen receptor signaling in a mouse model of obesity-associated PCOS

Abstract Background Obesity-associated polycystic ovary syndrome (PCOS) is characterized by metabolic dysfunction, adipose inflammation and androgen excess, but the adipose mechanism linking metabolic stress to androgen-related pathology remains unclear. This study aimed to deter...