Chun Ling Zhao

Bidirectional Mediation Effects of Body Mass Index and Inflammatory Markers on Assisted Reproductive Outcomes in Women With Polycystic Ovary Syndrome

OBJECTIVE: To evaluate the bidirectional mediation effects of body mass index (BMI) and inflammatory markers (neutrophil-to-lymphocyte ratio [NLR], systemic immune-inflammation index [SII], platelet-to-lymphocyte ratio [PLR]) on assisted reproductive technology (ART) outcomes in...

Lipid-related metabolic indices and in vitro fertilization outcomes in women with polycystic ovary syndrome: a retrospective cohort study with mediation analysis

To examine the association between composite lipid-related metabolic indices and embryological outcomes in women with polycystic ovary syndrome (PCOS) undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), and to test whether body mass index (BMI) and seru...

Proteomic and metabolomic alterations in follicular fluid associated with embryological outcomes in women with isolated ANA-positive infertility: a prospective multi-omics cohort study

Autoimmune abnormalities are increasingly recognized as contributing factors to unexplained infertility. Among these, antinuclear antibodies (ANAs) are the most frequently detected autoantibodies and have been associated with adverse embryologic outcomes. However, the mechanisms...