Chun-Chun Chang

Development of multiplex real-time polymerase chain reaction assay for the detection of leukemia-associated translocation genes

A BSTRACT Objective: Leukemia diagnosis involves diverse methods, including cytomorphology, flow cytometry, cytogenetics, and molecular diagnostics. While cytogenetics plays an indispensable role, it is limited by a high false-negative rate. In contrast, molecular diagnostics, su...