Chubiao Zhuo

circTNS3 accelerates bladder outlet obstruction-induced bladder remodeling by amplifying cGAS-STING signaling via the miR-510-5p/cGAS axis

Abstract Background Bladder outlet obstruction (BOO) induces progressive bladder remodeling through sustained intravesical pressure overload, leading to structural and functional impairment. Circular RNAs (circRNAs) play critical regulatory roles in diverse physiological and path...