Chu-Hong Fang

Curvulinic Acid−Clavatol Hybrids and Curvulinic Acid Dimers with Anti-Inflammatory Activity from Penicillium sp. KYS-21

Abstract A chemical investigation of the fermentation broth of the soil-derived fungus Penicillium sp. KYS-21 led to the isolation of seven previously undescribed polyketide metabolites (1−7). Among them, penicurclavones A−D (1−4) represent the first examples of curvulinic acid−c...