Christopher A. LeClair

RNF5 Regulates HERP1 and OS9 Stability and Modulates Processing of an ERAD Substrate

Endoplasmic reticulum-associated degradation (ERAD) must dynamically adapt to cellular protein-folding demands, yet mechanisms regulating ERAD-associated adaptors remain incompletely defined. Here, we identify the E3 ubiquitin ligase RNF5 as a regulator of the ERAD adaptors HERPU...