Christoph H. Borchers

ALY688 Protects Against Myocardial Ischemia‐Reperfusion Injury via Direct Effects and Rab8a‐Dependent Extracellular Vesicles

ABSTRACT Despite advances in percutaneous coronary intervention, ischemia‐reperfusion (IR) injury remains a major cause of morbidity and mortality. Adiponectin confers broad cardioprotective effects, motivating the development of adiponectin receptor agonists. Here, we investigat...

OvercomingElectrochemiluminescence Immunoassay (ECLIA)Limitations: Conformation-Independent Quantitation of a TherapeuticAntibody by LC–MS/MS

Abstract Monoclonal antibody therapies have transformed cancer treatment by enabling targeted intervention even in advanced disease stages. However, reliable monitoring of circulating therapeutic antibody levels is critical to ensuring efficacy and patient safety. This study inve...