Chris Zhiyi Zhang

Proximal ProteomicsReveals Potential Regulators ofProgrammed Death-Ligand 1 in Human Cancer

Abstract Programmed death-ligand 1 (PD-L1) is a key mediator of tumor immune evasion, but the protein networks governing its post-translational regulation remain incompletely understood. Here, we used PhastID-based proximity labeling to map the PD-L1 proximal proteome and integra...