Chongling Sun

An Extravasation-on-Chip Integrating Mechanical Measurements for Post-Extravasation Metastatic Pathways Study

Abstract Tumor cells (TCs) typically achieve brain metastasis through two distinct post-extravasation routes: invasion into the parenchyma or migration along the abluminal surface of vessels. However, the biomechanical cues dictating this route selection remain poorly understood....