Chenxin Zhu

The Lactate–Lactylation Axis as a Metabolic–Epigenetic Framework for Therapeutic Adaptation in Esophageal Squamous Cell Carcinoma

Therapeutic failure in esophageal squamous cell carcinoma (ESCC) can arise as tumor cells and their microenvironment adapt to sustained treatment pressure. The lactate–lactylation axis may connect altered metabolism with adaptive treatment responses through changes in protein and...

Global distribution of lung cancer staging at diagnosis: a systematic review

Lung cancer remains the leading cause of cancer-related mortality worldwide, with stage at diagnosis significantly influencing survival outcomes. This systematic review evaluates global variations in lung cancer stage distribution at diagnosis and examines the associations of soc...