Chenxia Zhou

Association between central thyroid hormone dysregulation and chronic kidney disease in type 2 diabetes: a cross-sectional study

This cross-sectional study investigated the association between central thyroid hormone resistance and chronic kidney disease (CKD) in patients with type 2 diabetes mellitus (T2DM) who have normal peripheral thyroid hormones. The study included 2,759 T2DM patients with normal ser...

Targeting Mitochondrial Complex I Protects Against Palmitic Acid–Induced Endothelial Dysfunction

ABSTRACT Background Endothelial dysfunction induced by elevated free fatty acids is a critical initiating event in diabetic macrovascular complications. While mitochondrial reactive oxygen species (mtROS) are key mediators of this lipotoxic injury, the specific contribution of mi...