Cheng-Tso Tsai

Species-Dependent Citrus–Simvastatin Interaction Profiles in an Acute Rat Model: Integrating Drug Disposition, Hepatic Redox, and Complementary Computational Analysis

Abstract Citrus species differ widely in flavonoid chemistry, yet grapefruit has come to represent the genus in citrus–statin interactions. To test whether this translates into species-dependent interaction profiles, six flavonoid-profiled citrus peel extracts (Citrus limon, C. d...