Chaowei Shi

Monofluoromethylphenylalanine: A Sensitive 19F Probe for Protein Conformational Dynamics In Vitro and in Cells

Abstract The combination of site-specific incorporation of 19F-labeled unnatural amino acids (UAAs) and 19F nuclear magnetic resonance (NMR) spectroscopy is a powerful strategy for investigating protein structure, dynamics, and interactions. However, commonly used 19F-containing...