Chao Bian

Comparative Genomics Reveals Diversification and Chromosomal Organization of Putative Antimicrobial Peptide-Derived Sequences in Amphibious Mudskippers

Antimicrobial peptides (AMPs) and AMP-like fragments are important components of vertebrate innate immunity, but their genome-wide diversification in amphibious fishes remains unclear. Here, we performed integrated bioinformatics and comparative genomic analyses of three represen...

Single‐Cell Transcriptomics and Metabolomics Reveal Glutamate Dehydrogenase as a Central Regulator of Nitrogen Metabolic Remodeling During Alkalinity Adaptation in Crustaceans

ABSTRACT Alkaline environments disrupt ammonia excretion and challenge nitrogen metabolism in aquatic invertebrates, but the underlying cellular mechanisms remain unclear. To elucidate the adaptive mechanisms of crustaceans in highly alkaline environments, the responses of Macrob...