Author
Changyuan Hu
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Recent research
- BiologyOpen access
EPHA2 and WNT reciprocally regulate MAPK-dependent gene expression in a pancreatic cancer model
Wnt signaling drives tumorigenesis in multiple cancers, in part through complex interactions with other oncogenic pathways including the MAPK cascade. In Wnt-addicted cancers, pharmacologic and genetic inhibition of Wnt signaling activates multiple receptor tyrosine kinases (RTKs...