Changkun Liu

Decoding hypoxia-driven microenvironment remodeling in bladder cancer reveals TPST1 as a key driver of metastasis

Hypoxia is a key feature of the bladder cancer tumor microenvironment, but its cellular organization, prognostic value, and functional effectors remain incompletely defined. Here, we integrated single-cell RNA sequencing, bulk transcriptomic cohorts, machine-learning modeling, im...