Chang Yao

Nicotinamide Metabolism Constrains Memory CD8 + T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐bin...