Chang-Chung Tsou

Hyperglycemia induces endothelial mitochondrial dysfunction and myeloperoxidase dysregulation in PCOS iPSCs

Polycystic ovary syndrome (PCOS) is associated with increased risks of cardiovascular disease (CVD), driven in part by endothelial dysfunction. Using patient-derived induced pluripotent stem cells (iPSCs), we established an endothelial model to examine cellular responses to metab...