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Intrahippocampal thyroid hormone administration modulates metaplasticity via Tau phosphorylation in PTU-induced hypothyroid rats

Abstract This study investigates the influence of thyroid hormones—triiodothyronine (T3) and thyroxine (T4)—on hippocampal metaplasticity and Tau phosphorylation under hypothyroid conditions. Employing electrophysiological assessments and biochemical analyses, we demonstrate that...