Cassie Overstreet

POWER, REPLICATION, AND EPIGENETIC SIGNAL IN PSYCHIATRIC DISORDERS: CONTRASTING METHYLOME-WIDE ASSOCIATION STUDIES OF MAJOR DEPRESSIVE DISORDER AND GENERALIZED ANXIETY DISORDER IN THE MILLION VETERAN PROGRAM

Epigenome-wide association studies (EWAS) of psychiatric disorders have historically been limited by modest sample sizes, contributing to inconsistent findings and poor replication. Leveraging DNA methylation data from the Million Veteran Program (MVP), we conducted large-scale m...