Carsten Spitzer

Using multi-trait polygenic scores to predict lithium responsiveness in patients with bipolar disorder

Background The predictive power of polygenic scores (PGSs) for lithium treatment response in bipolar disorder remains limited. Aims To enhance the prediction of lithium responsiveness by developing a multi-trait PGS (mt-PGS) combining genetic information from multiple phenotypes...

Associations Between Dissociation and Childhood Trauma in Borderline Personality Disorder and Affective Disorders: A Network Analytic Approach

ABSTRACT Background Dissociation and childhood trauma are strongly associated with borderline personality disorder (BPD), yet it remains unclear whether this reflects disorder‐specific mechanisms or differences in symptom severity within a shared transdiagnostic structure. Object...