Carlos Augusto Finelli

Pilot evaluation of pathogen isolation using targeted amplicon next-generation sequencing on sonication fluid for the diagnosis of periprosthetic joint infections

Abstract Background Periprosthetic joint infection (PJI) remains difficult to diagnose due to the limited sensitivity of conventional culture, which frequently yields false-negative results. Targeted amplicon next-generation sequencing (tNGS) offers a method capable of identifyin...