Caichen Zhong

Risk of orofacial clefts in offspring following maternal exposure to anti-seizure medications in a UK CPRD GOLD observational study

Abstract Orofacial clefts (OFC) are complex congenital anomalies characterised by a gap in the upper lip and/or palate, causing speech and feeding difficulties in children. Studies suggest inconsistent findings for an association between anti-seizure medications (ASM) and OFCs. O...