Burkhard Koenig

Electron-Donor–AcceptorEnabled ElectrophilicC(sp2)-C(sp3) Cross-Coupling

Abstract The construction of C(sp2)-C(sp3) bonds is fundamental to pharmaceutical synthesis, yet metal-free approaches to electrophilic cross-coupling remain underdeveloped. Herein, we report a visible-light-driven, metal-free cross-coupling between heteroaryl nitriles and alkyl...