Author
Burak Kuzu
Recent research
- Health & MedicineOpen access
Objective: Type 2 diabetes is a global health problem marked by chronic hyperglycemia. α-Glucosidase inhibitors help regulate postprandial glucose levels, but current drugs have side effects and limited efficacy. This study aimed to develop novel pyrazole–barbiturate hybrids as m...
- Health & MedicineOpen access
Quinine modulates PD-L1 and STAT3 in MCF-7 cells: An in silico and in vitro study
Programmed death-ligand 1 (PD-L1) overexpression in cancer cells is linked to immune escape and tumor progression, with signal transducer and activator of transcription 3 (STAT3) as a key transcription factor regulating its expression. This study evaluates the potential of quinin...