Brittany E. Bannish

Effects of Fibrinogen and Thrombin Concentrations on Clot Structure and Internal Clot Lysis Time

Background: In the final steps of the coagulation cascade, thrombin converts fibrinogen to fibrin, which polymerizes into a fibrin network that stabilizes blood clots. The concentration of these two proteins can affect network structure. The fibrin network is dissolved by plasmin...