Brigita Gradauskienė

Lipopolysaccharide and cytokine levels differ by disease severity in major depressive disorder

Abstract Background Major depressive disorder (MDD) lacks established biological markers, although immune dysregulation and gut-derived inflammation have been implicated in a subset of patients; however, their diagnostic utility across levels of depression severity and impact of...

Beyond Swelling: Clinical Insights into the Diagnosis and Management of Hereditary Angioedema

Hereditary angioedema (HAE) is a rare genetic disorder characterized by recurrent episodes of severe, non-pitting edema, most commonly caused by a deficiency or dysfunction of C1 esterase inhibitor (C1-INH), resulting in excessive bradykinin production. HAE subtypes differ accord...