Brian K. Lee

Risk of orofacial clefts in offspring following maternal exposure to anti-seizure medications in a UK CPRD GOLD observational study

Abstract Orofacial clefts (OFC) are complex congenital anomalies characterised by a gap in the upper lip and/or palate, causing speech and feeding difficulties in children. Studies suggest inconsistent findings for an association between anti-seizure medications (ASM) and OFCs. O...

Antidepressant Prescribing Trends for Adults With and Without Autism in the United Kingdom From 1997 to 2023: A Population‐Based Cohort Study Using Clinical Practice Research Datalink Aurum

Antidepressant prescribing and autism diagnoses have increased in recent years. We aimed to describe and compare trends in antidepressant prescribing, indications, doses and durations in autistic and non-autistic males and females in the United Kingdom (UK) from 1997 to 2023. Usi...