Brian F. Emrick

Alterations of endothelial cell bioenergetics in congenital diaphragmatic hernia

Abstract Background Pulmonary vascular development in congenital diaphragmatic hernia (CDH) is characterized by impaired angiogenesis and pathologic remodeling that contribute to pulmonary hypertension/hypoplasia. Mitochondria regulate endothelial energy, redox balance, and angio...