Brendan W. Wren

A modular constitutive single-plasmid platform for efficient production of a recombinant Strep A glycoconjugate vaccine

Abstract Production of glycoconjugate vaccines has long relied upon chemical methods which are highly complex and expensive, resulting in vaccines that are not widely affordable. Heterologous bioconjugation methods, such as Protein-Glycan Coupling Technology (PGCT), have emerged...