Boobalan Duraisamy

Molecular Rewiring and Compensatory Mechanisms Sustain DNA Recognition in the Mutant ZTA Transcription Factor: Insights from Molecular Dynamics Simulations

Abstract Protein–DNA complexes are stabilized by various interactions through an interaction network between protein and DNA. Any change in the system─whether through mutations in protein/DNA, external factors, or protein conformational transitions─can alter the interaction netwo...