Bo Yu

The IGF2BP3/circDock1/TCF21 axis relieves chronic cerebral ischemic injury by regulating neuronal ferroptosis

Ferroptosis, a form of cell death driven by iron and lipid damage, exacerbates brain injury during chronic cerebral ischemia. However, its precise regulatory mechanisms remain poorly understood. Here we show that the RNA-binding protein IGF2BP3 suppresses neuronal ferroptosis in...